Effects of Long-Term Dietary Protein Restriction on Intestinal Morphology, Digestive Enzymes, Gut Hormones, and Colonic Microbiota in Pigs

Effects of Long-Term Dietary Protein Restriction on Intestinal Morphology, Digestive Enzymes, Gut Hormones, and Colonic Microbiota in Pigs

Blog Article

Using protein-restriction diets becomes a potential strategy to save the dietary protein resources.However, the mechanism of low-protein diets influencing pigs’ growth performance is still controversial.This study aimed to investigate the effect of protein-restriction diets on gastrointestinal physiology and gut microbiota in pigs.

Eighteen weaned piglets were randomly allocated to three groups with different dietary protein levels.After a 16-week trial, the results showed cashel tail bag that feeding a low-protein diet to pigs impaired the epithelial morphology of duodenum and jejunum (p < 0.05) and reduced the concentration of many plasma hormones (p < 0.

05), such as ghrelin, somatostatin, glucose-dependent insulin-tropic polypeptide, leptin, and gastrin.The relative abundance of Streptococcus and Lactobacillus in colon and microbiota metabolites was also decreased by extreme protein-restriction sukin body lotion woolworths diets (p < 0.05).

These findings suggested that long-term ingestion of a protein-restricted diet could impair intestinal morphology, suppress gut hormone secretion, and change the microbial community and fermentation metabolites in pigs, while the moderately low-protein diet had a minimal effect on gut function and did not impair growth performance.